| What is Indomethacin?
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Indomethacin is a nonsteroidal anti-inflammatory drug and is used to relieve the inflammation, swelling, stiffness and joint pain associated with moderate or
severe rheumatoid arthritis and osteoarthritis, and ankylosing spondylitis. It is also used to treat bursitis, tendinitis, acute gouty arthritis, and other kinds of pain. |
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| Are there any side effects associated with Indomethacin?
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Indomethacin side effects may include abdominal pain, constipation, depression, diarrhea, dizziness, fatigue, headache, heartburn, indigestion, nausea, ringing in the ears, sleepiness or excessive drowsiness, stomach pain, stomach upset, vertigo,
and vomiting.
If the side effects continue or are bothersome, check with
your doctor. Less common or rare Indomethacin side effects may include
anemia, anxiety, asthma, behavior disturbances, bloating, blurred vision, breast changes, changes in heart rate, chest pain, coma, congestive heart failure, convulsions, decrease in white blood cells, fever, fluid in lungs, fluid retention, flushing, gas, hair loss, hepatitis, high or low blood pressure, hives, itching, increase in blood sugar, insomnia, kidney failure, labored breathing, light-headedness, loss of appetite,
mental confusion, muscle weakness, nosebleed, peptic ulcer, problems in hearing, rash, rectal bleeding, Stevens-Johnson syndrome, stomach or intestinal bleeding, sweating, twitching, unusual redness of skin, vaginal bleeding, weight gain,
worsening of epilepsy, and yellow eyes and skin. |
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| How is Indomethacin taken?
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Follow the directions for taking Indomethacin provided by your doctor. Indomethacin
should be taken with food or an antacid, and with a full glass of water. Never take on an empty stomach. If you are using
Indomethacin for arthritis, it should be taken regularly. If you are taking the liquid form of this medicine, shake the bottle well before each use.
Capsules should be swallowed whole, not crushed or broken. Do not lie down for about 20 to 30 minutes after taking
Indomethacin. This helps prevent irritation that could lead to trouble in swallowing. If you are using the suppository form of this
medicine and if the suppository is too soft to insert, hold it under cool water or chill it before removing the wrapper.
Remove the foil wrapper and moisten your rectal area with cool tap water.
Lie down your side and use your finger to push the suppository well up into the rectum. Hold your buttocks together for a few seconds.
Indomethacin suppositories should be kept inside the rectum for at least 1 hour so that all of the medicine can be absorbed by your body.
If you miss a dose take the forgotten dose as soon as you remember. If it is time for your next dose, skip the one you missed and return to your regular schedule.
Do not take
two doses at once. |
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| Are there any effects of taking Indomethacin with other medications?
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Some medicines may interact with Indomethacin. Inform your doctor of all prescription and over-the-counter medicine that you are taking.
It is especially important to check with your doctor before combining
Indomethacin with aspirin, beta-blockers, blood-thinning medicines,
captopril, cyclosporine, diflunisal, digoxin, lithium, loop diuretics,
other nonsteroidal anti-inflammatory drugs, potassium-sparing water pills,
probenecid, the anticancer drug methotrexate, thiazide-type water pills,
or triamterene. |
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| How should I store Indomethacin?
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Store Indomethacin at room temperature in a tightly closed container, away from heat and light. |
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